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What is Brukinsa (zanubrutinib) used for? 1 bottle with 120 capsules of 80 mg
- Mantle cell lymphoma (MCL) after at least one prior therapy
- Advanced marginal zone lymphoma (MZL) for people who didn’t respond well to other anticancer medications
- Waldenström macroglobulinemia (WM)
- Chronic lymphocytic leukemia (CLL) and small lymphocytic leukemia (SLL)
- Advanced follicular lymphoma (FL)
| Usage/Application | Hospital | |
| Compostion | Zanubrutinib 80 mg | |
| Brand Name | Brukinsa 80 mg Capsule | |
| Usage |
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Size Guides ![Image]()
SIZE GUIDE
JEANS
| SIZE | XS | S | M | L | XL | XXL |
|---|---|---|---|---|---|---|
| BUST | 88 | 89 | 90 | 91 | 92 | 93 |
| WAIST | 55 | 56 | 58 | 59 | 62 | 65 |
| HIPS | 90 | 92 | 94 | 95 | 96 | 98 |
T-SHIRTS
| SIZE | XS | S | M | L | XL | XXL |
|---|---|---|---|---|---|---|
| BUST | 60 | 62 | 65 | 66 | 68 | 69 |
| WAIST | 50 | 55 | 58 | 62 | 65 | 66 |
| HIPS | 80 | 82 | 85 | 86 | 88 | 89 |
Delivery and return
Delivery and return
RETURN POLICYWe do not offer refunds at this time. Organic by John Patrick offers exchanges or store credit only within 10 days upon receipt of goods. All discounted items are final sale, no exchanges. FOR EXCHANGES ONLYKindly, be as considerate as possible when it comes to exchanges. Items must be in original packaging, unused condition with original tags intact. We will ship you the exchanged items if they are available or you will be sent an electronic gift card. Any exchange requests falling outside of the 10 day time frame outlined above will not be accepted. Items returned without a return authorization will be refused. SALE PURCHASESALL SALE ITEMS ARE FINAL SALE. NO RETURNS OR EXCHANGES. INTERNATIONAL PURCHASESINTERNATIONAL SALES ARE FINAL SALE. NO RETURNS OR EXCHANGES. When shipping to international addresses, you will be responsible for import duties, fees and taxes upon delivery of your international order. This charge is determined by your local customs authority. We suggest contacting your local customs office for additional information on these charges.
Shipping Information
Shipping Information
Free Standard Shipping on Domestic (United States) orders. Free International Shipping on orders over $300.00. All International Orders must pay all custom and clearance related duties and taxes. Failure to do so will forfeit your ability to return your order. 2nd Day Air ($50) and Overnight ($100) is available to the continental US, must be placed before 1:30PM Eastern Time on a business day or it will ship out the next business day. International shipping for minimum orders of $150.00 is available for $50.00. We ship using UPS Express Saver for International shipping. Most orders are shipped by the next business day after they are placed. We will send you a shipping confirmation email to your provided email address when all or part of your order is shipped, which will include the tracking number. Domestic orders usually deliver within 5-7 business days. International orders usually deliver within 7-14 business days.
Composition and care
Composition and care
| Size | US | UK / AUS | France | Italy | Japan | Denmark |
|---|---|---|---|---|---|---|
| XS | 0-2 | 6 | 34 | 38 | 5 | 32 |
| S | 2-4 | 8 | 36 | 40 | 7 | 34 |
| M | 6-8 | 10 | 38 | 42 | 9 | 36 |
| L | 8-10 | 12 | 40 | 44 | 11 | 38 |
Description
Brukinsa (zanubrutinib) is a Bruton’s Tyrosine Kinase (BTK) inhibitor indicated for the treatment of adult patients with Mantle Cell Lymphoma (MCL), Waldenström’s Macroglobulinemia (WM), relapsed/refractory Marginal Zone Lymphoma (MZL).
Brukinsa (zanubrutinib) was approved by the FDA in November 2019 and by the EMA in November 2021.
Shipping
Room temperature shipping
For this medication, standard shipping applies. This means that a consistent room temperature of 15 to 25°C is maintained during transit.
BRUKINSA is an anticancer medicine that contains the active substance zanubrutinib. It belongs to a class of medicines called protein kinase inhibitors. This medicine works by blocking Bruton’s tyrosine kinase, a protein in the body that helps cancer cells grow and survive
How Brukinsa (zanubrutinib) works
There’s a pathway inside some cells called the Bruton tyrosine kinase pathway, that sends signals that tell cells to grow and divide. This pathway is particularly active in B-cell cancers such as mantle cell lymphoma and chronic lymphocytic leukemia.
Brukinsa (zanubrutinib) is a Bruton’s tyrosine kinase (BTK) inhibitor. It blocks a specific protein in the Bruton tyrosine kinase pathway so that the cancer cells can’t grow or spread as well.
Drug Facts
Common BrandsBrukins
Drug ClassBruton’s tyrosine kinase (BTK) inhibitor
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
What are the side effects of Brukinsa (zanubrutinib)?
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Higher blood sugar levels (55%)
- Low blood cell counts, all (up to 50%)
- Muscle or joint pain (up to 45%)
- Cough, runny nose, and other symptoms of an upper respiratory tract infection (up to 44%)
- Bleeding (up to 42%)
- Rash (up to 36%)
- Higher creatinine levels (34%)
- Tiredness (up to 31%)
- Higher liver enzyme levels (up to 28%)
- Changes in electrolyte levels (up to 27%)
- Diarrhea (up to 25%)
- Higher potassium levels (24%)
- Bruising (up to 24%)
Other Side Effects
- Nausea
- Headache
- Fever
- Constipation
- Vomiting
- Itching
- Dizziness
- Swelling in the hands and feet
Note: These side effects were reported by people in clinical trials for MCL, MZL, or WM.
Serious Side Effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious infections: body aches, chills, fever, headache, new cough, sore throat, feeling tired, lowered blood cell counts
- Serious bleeding (general): bleeding or bruising that doesn’t stop or go away, large amount of bleeding, blood in the urine, throwing up blood, bloody or black and tarry stool
- Brain bleeds: headache, weakness, changes in vision, nausea, vomiting, trouble speaking or understanding speech, difficulty maintaining balance
- Stomach bleeds: dizziness, trouble breathing, feeling faint, stomach pain, nausea, vomiting, bright red blood in vomit, dark and tarry stool
- Heart rhythm problems: fainting, dizziness, chest pain, fast heartbeat, dizziness, difficulty breathing
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